📗 -> 01/07/25: BIM280-L1
[Lecture Slide Link]
🎤 Vocab
❗ Unit and Larger Context
Intro to Braiin - Neuroanatomy and Neural Cicuits
Neurophysiology
BMI Applics - Chapin, Moxon et al.
✒️ -> Scratch Notes
Rat recordings of pressing lever
Using recordings to detect future ressings
PCA as a neural op funct
Robot arm hard, have to account for momentum and intertia
2024 Braingate: RNN for mullti cursor control
Posterior Parietak cortex (PPC)
- Transforming viz info into motor commands
M1, Premotor corttex, supplementary motor area (SMA)
Corticospinal Tract (pyramidal track)
- descending pathway for voluntary movement humans
- axons: m1, SMA, premotor are fibers making tract
- only direct pathway from cortex to the spine
-
million fibers
-
Subcortical Structures
- Striatum
- Collective name for several structure
- Important in BG
- Parkinsons, disfunction in dopamine response
- Globus Pallidus
- Substatia nigra
- Thalamus
- “Relay station”
- relays info from sbcortical areas and the cortex
Pathways
Info transmitted multiple loops. Very confusing and interconnected, this is mostly for our understanding. None really seperate.
Motor Loops
Oculomotor Loop
Prefrontal Loop
Limbic Loop
Spinal Cord
Corticospinal Tract (CST) main pathway for voluntary control.
compsed of both white and gray matter.
“Butterfly pattern” / Crosss section of spinal cord resembles it
- Grey matter (cell bodies), White matter (axons), white becausue myelin sheath.
Ventral Horn of the spine?
Muscle
Eventually, the end goal of pathways will be motor activation.
Involuntary Motor Control - Handled by other networks, like the brain stem. and the pons.
- Breathing
- Heart rate
- Blood pressure
- Body temperature
Modeling - Needs to simplify phenomena, while retaining acuracy. If no assumptions, then its just the original system.
EX:
- In order to control voluntary movements
Hist of Neural control
Wilder Penfield (1930s) - Montreal Procedure
- Inactivating cortex, and seeing if its critical before insicion
- Used to explor emotor homonculus
At the same time, a lot of work in exploring the implications of neurnsn have electrical signal
- 1875 Caton EEG
- 1926 Adrian first neural activity: discovery of AP
- 1952 Hodkin and Huxley understanding mechanisms of AP
- Nonlinear equations based on work with giant squid axon
- 1969 Evarts: Neuron encoding neural control info
- 1970 Humphrey et al.: Multiple single neuron recording
Logan TA takeover
Going over HW worksheet
🧪 -> Refresh the Info
Did you generally find the overall content understandable or compelling or relevant or not, and why, or which aspects of the reading were most novel or challenging for you and which aspects were most familiar or straightforward?)
Did a specific aspect of the reading raise questions for you or relate to other ideas and findings you’ve encountered, or are there other related issues you wish had been covered?)
🔗 -> Links
Resources
- Put useful links here
Connections
- Link all related words