Dataview

LIST
FROM #Collection
WHERE file.name = this.Entry-For

Insert entry name

🎤 Vocab

❗ Information

Small summary

✒️ -> Scratch Notes

Current Treatments

Psych Disorders:

Medication and psychotherapy (SSRIs, CBT)
Neurodegenerative Diseases
Managing symptoms primarily
- Drugs, therapies, lifestyle modifications
No know cures :(

Technology and BCIs

Neuroprosthetics:

Robotic arm
Cochlear implants

Neuralink

Neurological Disorders:

Parkisons, epilepsy
BCI/BMI, for paptients with drug-resistant epilepsy
Interrupr or even preent seizures

Brain Injuries/Stroke

Record brain signals, send to external device, and deliver appropriate isgnals to desired muscles

Cognitive Abilities

Improve memory, learning, decision making
Remote communication by using brain activity to control devices

Pros:

Improve accessibility for people with disabilities and neurological disorders
Improved ability to learn and process info
Cons:
Imprecise
- Cannot detect single neuron activity, only group activity at present
No long term research
Expensive

Deep Brain Stimulation

DBS

Electrodes implanted near key regions of the brain
Meant to correct brain activity

DBS treats:

Parkisons
Tremors
Epilepsy
OCD, tourettes
and more!

Pros:

Reduces symptoms
Reduces need for medication
Potential for long term improvements
Cons:
Invasive
Results not immediate
Usually a last resort

Neurofeedback for Autism

Neurofeedback:

Non-invasive EEG therapy
Brainwave monitoring with EEG sensors
Visual/Auditory cues provide feedback

Potential benefits:

Improved attention and focus etc.
Limitations
Range of responses
Vary between individuals
Accessibilitty and cost

VR therapies

Originally used for phobia treatments, but now can be used for PTSD, social and emotional skills, and anxiety and deppresion
Pros:

More mobile
More confidential
Cons:
Data privacy
Can be expensive
Technical
Difficult

Ultrasound for Alzheimer’s

Pathtology:

Accelerated buildup of amyloid plaque and tau proteins -> inefficient connections
- Disrupts neural signals
  Treatment:
Amyloid antibody immunotherapies (Aducanumab)
- Helps the brain’s natural immune cells (microglia) clear amyloid plaques more effectively

Problem:

Hard to get medicine to the affected area
- Blood Brain Barrier (BBB)
  Solution
Use low intensity focused unltrasound in conjunction with microscopic air bubles to temporarily open the BBB
- Sound waves create little gaps in the BBB
If used after injection of immunotherapy drugs, reduction in amyloid plaque is signficiantly increased
- More medicine delivered to the area

Prenatal EO Alzheimer’s Detection

How it’s done:

Pregnant patient goes through genetic testing
- Indicated for patients with a family history of EO AD
Presence of Apolipoprotein E -> significant chance (40-65%) that embryo will develop Alzheimer’s

Wegovy and Ozempic

Semaglutide mimics GLP-1 (hormone regulating blood sugar)
Semaglutide vs. other antidiabetic drugs on neurological/psychological outcomes:

Not associated with increased risk for most conditions
May be associated with decreased cognitive decline
Some studies show improved learning ability and decreased amyloid plaques in mice

Psychedelic Therapies

Induce neuroplasticity

Rapid increase in synaptogenesis after small doses
Treat stress disorders that cause loss of dendritic spines
TR depression, OCD, PTSD, etc.

🧪 -> Refresh the Info

Did you generally find the overall content understandable or compelling or relevant or not, and why, or which aspects of the reading were most novel or challenging for you and which aspects were most familiar or straightforward?)

Did a specific aspect of the reading raise questions for you or relate to other ideas and findings you’ve encountered, or are there other related issues you wish had been covered?)

Vault

Explorer

NT-Emerging-Neurotherapies