📗 -> 01/16/25: ECS124-L4
[Lecture Slide Link]
🎤 Vocab
❗ Unit and Larger Context
Covered optimal alignment last time
and
Visualized as a traceback array:
Use letter i, j for match | Space against char i |
|---|---|
Space against char j |
| 0 | 1 | 2 | 3 | |
|---|---|---|---|---|
| 0 | <— | <— | /\ | | |
| 1 | /\ | | |||
| 2 | |\ \ | |||
| 3 | X | |||
| This traceback array indicates the following optimal alignment: |
- --- --- x(1) x(2) x(3)
- y(1) y(2) --- --- y(3)
✒️ -> Scratch Notes
Local Alignment: Goal is to find a single similar region
Global Alignment: Find the optimal alignment to maximize total matching
| G | C | C | A | T | A | ||
|---|---|---|---|---|---|---|---|
| 0 | 0 | 0 | 0 | 0 | 0 | ||
| G | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
| C | 0 | 0 | 2 | 1 | 0 | 0 | 0 |
| C | 0 | 0 | 1 | 3 | 2 | 1 | 0 |
| C | 0 | 0 | 1 | 2 | 2 | 1 | 0 |
| A | 0 | 0 | 0 | 1 | 3 | 2 | 2 |
🧪 -> Refresh the Info
Did you generally find the overall content understandable or compelling or relevant or not, and why, or which aspects of the reading were most novel or challenging for you and which aspects were most familiar or straightforward?)
Did a specific aspect of the reading raise questions for you or relate to other ideas and findings you’ve encountered, or are there other related issues you wish had been covered?)
🔗 -> Links
Resources
- Put useful links here
Connections
- Link all related words